Non mRNA Vax

Singapore could be getting Novavax vaccines - a non-mRNA vaccine which has demonstrated high efficacy against the COVID-19 virus - before the end of the year.

Health Minister Ong Ye Kung said on Thursday (Jun 24) that Singapore authorities had signed an advance purchase agreement with Novavax in January this year.

He said that the vaccine is still undergoing Phase 3 clinical trials, and Singapore is awaiting Novavax's application for regulatory approval while working closely with them.

Novavax has said that it is on track to file for emergency authorisation in the US and elsewhere in the third quarter of 2021.

"But we hope the vaccine supplies can arrive before the end of this year for those who want to take something that is non-mRNA," said Mr Ong at a COVID-19 multi-ministry task force press conference where he announced that the country will be ramping up its vaccination programme.

What is the Novavax vaccine and how is it different from other vaccines being used now? Here's what we know so far:

PROTEIN-BASED VACCINE

Novavax calls its approach recombinant nanoparticle vaccine technology, it has also been called a protein sub-unit vaccine.

The technology has been in use for two decades to make vaccines, including for whooping cough and shingles.

According to a CNN report, Novavax clones a modified version of the gene for the COVID-19 virus spike protein into a baculovirus that infects insects.

Scientists then infect moth cells with that virus, spurring them to produce the coronavirus spike protein. These virus-like nanoparticles are harvested to make the vaccine.

Sinovac uses the whole, deactivated virus, while vector vaccines, like AstraZeneca, use an adenovirus to carry genetic instructions for the human body to make the spike protein. mRNA vaccines like Pfizer-BioNTech and Moderna use pieces of genetic material called messenger RNA to instruct cells to make a piece of the coronavirus spike protein.

All of them have the same purpose - to stimulate the body to produce an immune response to the virus without actually causing illness.

The main difference between Novavax and the mRNA or vector vaccines is that it is made with lab-grown copies of the COVID-19 spike protein, whereas vector and mRNA vaccines include genetic instructions for the body to make its own spike protein.

Novavax requires two doses given 21 days apart and the vaccine is stable at 2 to 8 deg Celsius, which are standard refrigerator temperatures. This means that it will be easier to store and transport for low and middle-income countries.

HIGH EFFICACY

The Novavax jab is about 90 per cent effective against COVID-19 across a variety of variants of the virus.

In Phase 3 trials in the UK earlier this year, it was 89.3 per cent effective at preventing COVID-19 and around 86 per cent effective at protecting against the Alpha variant from the UK.

It was 95.6 per cent effective against the original COVID-19 strain.

https://www.channelnewsasia.com/news/singapore/novavax-vaccine-moths-spike-protein-covid-19-non-mrna-15088434

I may consider this.

Red Lily wrote:Singapore could be getting Novavax vaccines - a non-mRNA vaccine which has demonstrated high efficacy against the COVID-19 virus - before the end of the year.

Health Minister Ong Ye Kung said on Thursday (Jun 24) that Singapore authorities had signed an advance purchase agreement with Novavax in January this year.

He said that the vaccine is still undergoing Phase 3 clinical trials, and Singapore is awaiting Novavax's application for regulatory approval while working closely with them.

Novavax has said that it is on track to file for emergency authorisation in the US and elsewhere in the third quarter of 2021.

"But we hope the vaccine supplies can arrive before the end of this year for those who want to take something that is non-mRNA," said Mr Ong at a COVID-19 multi-ministry task force press conference where he announced that the country will be ramping up its vaccination programme.

What is the Novavax vaccine and how is it different from other vaccines being used now? Here's what we know so far:

PROTEIN-BASED VACCINE

Novavax calls its approach recombinant nanoparticle vaccine technology, it has also been called a protein sub-unit vaccine.

The technology has been in use for two decades to make vaccines, including for whooping cough and shingles.

According to a CNN report, Novavax clones a modified version of the gene for the COVID-19 virus spike protein into a baculovirus that infects insects.

Scientists then infect moth cells with that virus, spurring them to produce the coronavirus spike protein. These virus-like nanoparticles are harvested to make the vaccine.

Sinovac uses the whole, deactivated virus, while vector vaccines, like AstraZeneca, use an adenovirus to carry genetic instructions for the human body to make the spike protein. mRNA vaccines like Pfizer-BioNTech and Moderna use pieces of genetic material called messenger RNA to instruct cells to make a piece of the coronavirus spike protein.

All of them have the same purpose - to stimulate the body to produce an immune response to the virus without actually causing illness.

The main difference between Novavax and the mRNA or vector vaccines is that it is made with lab-grown copies of the COVID-19 spike protein, whereas vector and mRNA vaccines include genetic instructions for the body to make its own spike protein.

Novavax requires two doses given 21 days apart and the vaccine is stable at 2 to 8 deg Celsius, which are standard refrigerator temperatures. This means that it will be easier to store and transport for low and middle-income countries.

HIGH EFFICACY

The Novavax jab is about 90 per cent effective against COVID-19 across a variety of variants of the virus.

In Phase 3 trials in the UK earlier this year, it was 89.3 per cent effective at preventing COVID-19 and around 86 per cent effective at protecting against the Alpha variant from the UK.

It was 95.6 per cent effective against the original COVID-19 strain.

https://www.channelnewsasia.com/news/singapore/novavax-vaccine-moths-spike-protein-covid-19-non-mrna-15088434

I may consider this.

wouldnt you rather hemlock bark and frog toed stew?

If it really is a vaccination, it'll be banned quickly.

Not there, of course, but here. The Oligarch Lizard-Men NEED the Wu Flu. And the genetic engineering. And to demonstrate that they OWN us.

jirqoadai wrote:

Red Lily wrote:Singapore could be getting Novavax vaccines - a non-mRNA vaccine which has demonstrated high efficacy against the COVID-19 virus - before the end of the year.

Health Minister Ong Ye Kung said on Thursday (Jun 24) that Singapore authorities had signed an advance purchase agreement with Novavax in January this year.

He said that the vaccine is still undergoing Phase 3 clinical trials, and Singapore is awaiting Novavax's application for regulatory approval while working closely with them.

Novavax has said that it is on track to file for emergency authorisation in the US and elsewhere in the third quarter of 2021.

"But we hope the vaccine supplies can arrive before the end of this year for those who want to take something that is non-mRNA," said Mr Ong at a COVID-19 multi-ministry task force press conference where he announced that the country will be ramping up its vaccination programme.

What is the Novavax vaccine and how is it different from other vaccines being used now? Here's what we know so far:

PROTEIN-BASED VACCINE

Novavax calls its approach recombinant nanoparticle vaccine technology, it has also been called a protein sub-unit vaccine.

The technology has been in use for two decades to make vaccines, including for whooping cough and shingles.

According to a CNN report, Novavax clones a modified version of the gene for the COVID-19 virus spike protein into a baculovirus that infects insects.

Scientists then infect moth cells with that virus, spurring them to produce the coronavirus spike protein. These virus-like nanoparticles are harvested to make the vaccine.

Sinovac uses the whole, deactivated virus, while vector vaccines, like AstraZeneca, use an adenovirus to carry genetic instructions for the human body to make the spike protein. mRNA vaccines like Pfizer-BioNTech and Moderna use pieces of genetic material called messenger RNA to instruct cells to make a piece of the coronavirus spike protein.

All of them have the same purpose - to stimulate the body to produce an immune response to the virus without actually causing illness.

The main difference between Novavax and the mRNA or vector vaccines is that it is made with lab-grown copies of the COVID-19 spike protein, whereas vector and mRNA vaccines include genetic instructions for the body to make its own spike protein.

Novavax requires two doses given 21 days apart and the vaccine is stable at 2 to 8 deg Celsius, which are standard refrigerator temperatures. This means that it will be easier to store and transport for low and middle-income countries.

HIGH EFFICACY

The Novavax jab is about 90 per cent effective against COVID-19 across a variety of variants of the virus.

In Phase 3 trials in the UK earlier this year, it was 89.3 per cent effective at preventing COVID-19 and around 86 per cent effective at protecting against the Alpha variant from the UK.

It was 95.6 per cent effective against the original COVID-19 strain.

https://www.channelnewsasia.com/news/singapore/novavax-vaccine-moths-spike-protein-covid-19-non-mrna-15088434

I may consider this.

wouldnt you rather hemlock bark and frog toed stew?

Are you trying to kill me?

well no. thats the job of the US federal govt

Well this way is a hell of a lot easier than sending out Clinton wet Teams.

Red Lily wrote:I may consider this.

Why?

Lummy wrote:

Red Lily wrote:I may consider this.

Why?

Not to 'protect' me from Covid but because I want to travel and if getting a jab turns out to be the only way I'll be able to do that I'll consider the safest option in order to do so.

QUESTION:  Why are people's immune systems not tested prior to giving them a vax?
Cost?

That's a test I wouldn't mind getting, so long as I could trust the business giving it.